Rohypnol

Flunitrazepam, also known as Rohypnol among other names, is a benzodiazepine used in some countries to treat severe insomnia and assist with anesthesia. As with other hypnotics, flunitrazepam has been advised to be prescribed only on a short-term basis or by those with chronic insomnia on an occasional basis. It is a Schedule IV controlled substance in the United States.

It was patented in 1962 and came into medical use in 1974. Flunitrazepam has been referred to as a date rape drug, though the percentage of reported rape cases in which it is involved is small.

Rohypnol in Alpha and Omega
Brandon Nesbitt carried with him a vial of Rohypnol pills and a pill cutter. He would self-medicate himself when he needed to sleep especially to overcome the effects of jet lag. He knew that a whole tablet would knock him out for most of a day so he used the pill cutter to take a half or even a quarter pill depending on how soon he would need to wake up. He was also aware of how to use Roofies for other purposes but never need to apply the knowledge. On the trip to Tel Aviv, he dosed himself with a quarter pill and was out in minutes.